BE A PART OF RESEARCH!
https://bepartofresearch.nihr.ac.uk/
Join the Nova 301 Trial to find out if we can protect people 60 years of age or older against norovirus stomach bug symptoms
Enrolling Adults 60+: Help to see if we can protect people against symptoms caused by the norovirus stomach bug with an investigational mRNA vaccine
About the norovirus stomach bug
Norovirus is one of the most common stomach bugs in the UK. It can spread easily and most cases are often in care homes and schools. The norovirus stomach bug can cause many unpleasant symptoms like nausea, vomiting, and diarrhoea. Vulnerable people, such as children younger than age 5, adults older than age 60, and people with underlying health conditions, are at greater risk for serious symptoms of norovirus, which may require medical attention.
About the Nova 301 Trial
The Nova 301 Trial will see if an investigational vaccine (a vaccine that is being studied) may be able to prevent symptoms caused by the norovirus stomach bug from developing. The investigational vaccine in this clinical trial is called mRNA-1403. You cannot catch norovirus by having this investigational vaccine.
To participate in the Nova 301 Trial, you must:
• Be 60 years of age or older
• Be in good health
• Not currently have a chronic gastrointestinal disease (including IBS, colitis, oesophageal reflux, or any other medical condition where you have regular vomiting or diarrhoea)
What to expect
Your participation in the Nova 301 Trial will last up to 25 months.
• You will attend an initial screening visit, up to 6 additional clinic visits and up to 6 scheduled phone calls with the clinical trial team
• You will be given 1 jab, which will be either:
An investigational mRNA-1403 norovirus vaccine; OR A placebo jab (inactive substance)
• You must fill out an electronic diary (eDiary) regularly during your trial participation
• Enrolling in this clinical trial is completely your choice. You can leave at any time and do not have to give a reason
Moderna will reimburse participants for their trial-related time and expenses (for example, travel), and the clinical trial team are on hand to support everyone who takes part in the trial.
Call 01780781623 or email [email protected] at Wansford Research to find out more about joining the Nova 301 Trial, or click here
References:
1. NHS Inform. Norovirus. Accessed August, 2024. https://www.nhsinform.scot/illnessesand-conditions/infections-and-poisoning/norovirus/
2. GOV.UK. Norovirus cases increase significantly in England. Accessed August, 2024. https://www.gov.uk/government/news/norovirus-cases-increase-significantly-inengland
3. UK Health Security Agency. Norovirus: What to do if you catch it and helping to stop the spread. UK Health Security Agency. Accessed August, 2024. https://ukhsa.blog.gov.uk/2022/11/17/norovirus-what-to-do-if-you-catch-it-andhelping-to-stop-the-spread/
4. Lucero, Y. et al. Norovirus: Facts and Reflections from Past, Present, and Future. Viruses. 2021 Nov 30;13(12):2399. doi: 10.3390/v13122399